The task is now how do we look for it? Let's assume your respiratory physician works for the CIA, and your cancer's name is Osama.
Chest xray:The CIA can use satellites to take aerial photograph of Afghanistan (your lungs) hoping to see some shadows that resemble Osama. With some luck they may see some suspicious looking shadows wearing turban holding machine guns (lung nodules/lesion). Which may be Osama (harmful malignant nodule) or it could be just innocent small kids with toy gun (harmless benign nodule). To confirm it we need to extract that bugger out for confirmation. We need to biopsy it!
Biopsy via bronchoscope:
What they need now is to grab some of the lesion. Imagine your airways is like a network of caves. Now, if the lesion sits near the big airways a favourite option is to do insert a fexible endoscope via your nostrils/mouth into the airways and biopsy that lesion (send some agents into the caves and grab Osama to be sent to Guantanamo Bay for interogation. Trust me - doing the bronchoscope is really look like one is exploring a cave network.
CT scan-guided biopsy:
Boy! The CIA didn't realise that Osama doesn't play hoola hoop near the cave opening to be captured. He is hiding deep underneath the ground. So forget the caves onslaught. The CIA now has to drill the ground and send a covert team to kidnap Osama guided by special satellite image (CT scan).

Pleuroscopy:
Or if there is pleural effusion AKA 'abnormal fluid collection in the pleural cavity'. We can puncture the side of your chest and insert a flexible scope into the pleural cavity and suck the fluid out and biospy your pleural wall from inside... hmm something like the CIA can examine a river next to the cave plus some take some soil sample, hoping to find Osama's waste in the river which means he's there all along.
Oh all right that is a crap anology! So i'm gonna skip it and you guys just have to wait for Discovery channel.
Disclaimer:
The above anology is just for fun. If the CIA happen to read my blog. I'm neither working for Osama nor that I know where he is.
PS: Btw the CIA/Bush and Co. are bunch of moron who wouldn't know it even if Osama sleep in the White house over Thanksgiving.
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